Five gene variants in nonagenarians, centenarians and average individuals

INTRODUCTION: Genetic factors contribute to the variation of human life span which is believed to be more profound after 85 years of age. The aim of the present study was to evaluate the frequency of 5 gene polymorphisms between nonagenarians, centenarians and average individuals. MATERIAL AND METHODS: = 149 average lifespan individuals (control group aged 18 - < 80 years). RESULTS: = 0.017, respectively). CONCLUSIONS: gene polymorphisms. It seems that some polymorphisms may be significant in prolonging our lifespan. Nevertheless, confirmation in additional study populations is needed.