Key result
Five years of GH replacement therapy eliminated all baseline anthropometric and metabolic differences between adults with childhood-onset and adulthood-onset GH deficiency.
Why the study?
Does 5-year GH replacement therapy have different effects on body composition, muscle strength, bone mass, and metabolic indices in adults with childhood-onset versus adulthood-onset GH deficiency?
Cohort (n=42)
No
Does 5-year GH replacement therapy have different effects on body composition, muscle strength, bone mass, and metabolic indices in adults with childhood-onset versus adulthood-onset GH deficiency?
Five years of GH replacement therapy effectively eliminates baseline anthropometric and metabolic differences between adults with childhood-onset and adulthood-onset GH deficiency.
No takes yet. Share an insight, caveat, or question.
May support equivalent long-term GH replacement outcomes regardless of onset age; leaves open randomized confirmation before practice change.
Korányi et al. (2001) conducted a cohort in GH deficiency (n=42). Childhood onset GH deficiency vs. Adulthood onset GH deficiency was evaluated on Responses in body composition, muscle strength, bone mass, and metabolic indices. Five years of GH replacement therapy eliminated all baseline anthropometric and metabolic differences between adults with childhood-onset and adulthood-onset GH deficiency.
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