Key result
Subinvolution of the uteroplacental arteries resulted in the death of a 19-year-old woman 8 days postpartum, with microscopic evidence of partially occluding thrombi in dilated spiral arteries.
Case Report (n=1)
Subinvolution of the placental site can be a cause of delayed postpartum hemorrhage and significant morbidity or mortality.
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Alerts clinicians to subinvolution in fatal delayed postpartum hemorrhage; leaves open incidence, risks, and prevention strategies.
A 19-year-old G1P0 Caucasian woman died 8 days postpartum because of the subinvolution of the uteroplacental arteries. Microscopic examination of the placental implantation site revealed large, dilated spiral arteries containing partially occluding thrombi in the superficial myometrium. The presence of cytotrophoblasts within and surrounding the spiral arteries was confirmed by low molecular weight cytokeratin immunohistochemistry. Infection of the Cesarean section incision site was demonstrated by the growth of Staphylococcus aureus and Streptococcus agalactiae Group B in the wound as well as the intrauterine blood clot. Although subinvolution of the placental site may be a cause of delayed postpartum hemorrhage and significant morbidity, the underlying pathophysiologic mechanism is unknown.
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Farley et al. (2011) conducted a case report in Subinvolution of the uteroplacental arteries (n=1). Subinvolution of the uteroplacental arteries was evaluated on Death. Subinvolution of the uteroplacental arteries resulted in the death of a 19-year-old woman 8 days postpartum, with microscopic evidence of partially occluding thrombi in dilated spiral arteries.
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