The anticomplementary activity of compounds isolated from the heartwood of Caesalpinia sappan L. (Leguminosae) was investigated. The sterol mixture (campesterol 11.2%, stigmasterol 18.9% and beta-sitosterol 69.9%) was most potent and brazilin, brazilein, and protosappanin E showed a new anticomplementary activity on the complement system in vitro.
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Oh et al. (1998) studied this question.