Key result
Minimally invasive mitral repair with artificial chordae yields ~91% freedom from severe recurrent MR at 4 years.
Why the study?
The study was conducted to assess the efficacy of minimally invasive mitral valve repair using artificial chordae in managing primary mitral regurgitation and refining surgical techniques.
Does minimally invasive mitral valve repair using artificial chordae provide effective treatment in patients with severe primary mitral regurgitation?
Cohort (n=106)
No
Does minimally invasive mitral valve repair using artificial chordae provide effective treatment in patients with severe primary mitral regurgitation?
Minimally invasive mitral valve repair using artificial chordae demonstrates excellent midterm outcomes with high freedom from severe recurrent MR and low mortality.
Supports feasibility of MIMVR with artificial chordae in degenerative MR; hypothesis-generating pending randomized comparisons.
This study aims to assess the efficacy of minimally invasive mitral valve repair (MIMVR) using artificial chordae in managing primary mitral regurgitation (MR) and refining surgical techniques. We conducted a retrospective analysis at the Ho Chi Minh City University of Medicine and Pharmacy Hospital, involving 106 patients with severe MR due to degenerative valve disease, treated from March 2017 to June 2023. All patients underwent MIMVR via a minimally invasive right thoracotomy, utilizing artificial chordae. Detailed echocardiographic assessments were performed preoperatively, perioperatively, and during follow-ups, alongside the collection of operative data for statistical analysis. The study cohort was predominantly male (75.5 %), with an average age of 50.7 years. Fibroelastic deficiency was the primary cause of MR, affecting 83 % of patients. An average of 2.7 chordae pairs per patient was used, and the mean annuloplasty ring size was 30.7 mm. No in-hospital deaths or mitral valve-related reoperations were reported. At discharge, 88.7 % of patients exhibited normal or mild MR. During an average follow-up of 28.2 months, mortality was 1.9 %, and 1 % of patients required reoperation due to mitral valve issues. Kaplan–Meier analysis showed freedom from severe recurrent MR at 1, 2, and 4 years to be 97 %, 94 %, and 91 %, respectively. MIMVR using artificial chordae demonstrates promising midterm outcomes for severe MR, emphasizing the importance of surgical precision. Further studies should refine techniques and address complications to ensure long-term effectiveness in mitral valve repair.
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A 2025 study conducted a cohort in severe mitral regurgitation due to degenerative valve disease (n=106). Minimally invasive mitral valve repair (MIMVR) using artificial chordae was evaluated on freedom from severe recurrent MR at 4 years. Minimally invasive mitral valve repair using artificial chordae for severe mitral regurgitation achieved 91% freedom from severe recurrent MR at 4 years and a 1.9% mortality rate.
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