A highly fluorescent and efficient ratiometric ‘turn on’ probe for Hg2+ and Al3+ based on quinazoline (1) has been designed and synthesized. Limit of detection (LOD) and association constants revealed its superior binding affinity and sensitivity toward Hg2+ over Al3+. Interference studies signified displacement of the complexed Al3+ by Hg2+ which has been supported by various studies.
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Kumar et al. (2014) studied this question.