Key result
Deliberate artificial hyperventilation was immediately effective in preventing further arrhythmia and decreasing QRS complex width in a patient with severe tricyclic antidepressant poisoning.
Why the study?
Does deliberate artificial hyperventilation prevent further arrhythmia and decrease QRS width in a patient with severe tricyclic antidepressant poisoning?
Case Report (n=1)
Does deliberate artificial hyperventilation prevent further arrhythmia and decrease QRS width in a patient with severe tricyclic antidepressant poisoning?
Deliberate artificial hyperventilation may be an effective and immediate treatment for severe tricyclic antidepressant poisoning complicated by refractory ventricular fibrillation and wide QRS complexes.
Should not yet change practice in TCA poisoning; hypothesis-generating for hyperventilation in refractory arrhythmias.
A patient with severe tricyclic antidepressant poisoning who showed recurrent ventricular fibrillation and wide QRS complexes on the ECG, failed to respond to intravenous physostigmine and lidocaine. Deliberate artificial hyperventilation was immediately effective in preventing further arrhythmia and in decreasing the width of the QRS complexes. Hyperventilation, a neglected treatment, may be immediately effective in the treatment of severe tricyclic antidepressant poisoning.
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Michael Kingston (1979) conducted a case report in Severe tricyclic antidepressant poisoning (n=1). Deliberate artificial hyperventilation was evaluated on Prevention of further arrhythmia and decreasing the width of the QRS complexes. Deliberate artificial hyperventilation was immediately effective in preventing further arrhythmia and decreasing QRS complex width in a patient with severe tricyclic antidepressant poisoning.
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