Management of Tricyclic Antidepressant Ingestion in Children With Special Reference to the Use of Glucagon

Drug ingestion in young children is a constantly changing problem as new therapeutic agents become more frequently prescribed. A recent problem in children's hospitals arises from the popularity of tricyclic antidepressants. Ten cases are reported in which four of the patients were seriously affected, and one died. A plan of management and treatment is outlined with special emphasis on recognition of the serious low cardiac output and arrhythmic effects and on encouraging results following the use of glucagon.