Answers are grounded in this paper and cite their sources.
Two new cytotoxic trisoxazole macrolides, thiomycalolides A (2) and B (3), have been isolated from a marine sponge Mycale sp. The structures were determined to be glutathione adducts of mycalolides A and B by interpretation of spectral data and chemical transformation. Thiomycalolides A and B are highly cytotoxic against P388 murine leukemia cells.
No takes yet. Share an insight, caveat, or question.
Matsunaga et al. (1998) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: