Key result
Bifurcation stenting with 2 drug-eluting stents for coronary lesions was associated with a 26% rate of major adverse cardiac events at a mean follow-up of 22 months.
Cohort (n=124)
Treating coronary bifurcation lesions with a 2-stent drug-eluting stent strategy is associated with an acceptable long-term MACE rate, primarily driven by target vessel revascularization.
Supports 2-stent DES feasibility in bifurcations; leaves open optimal strategy versus provisional stenting in randomized trials.
There are little long-term clinical data regarding the safety and efficacy of using 2 drug-eluting stents (DESs) to treat coronary bifurcation lesions. We obtained clinical follow-up for 124 consecutive patients who underwent bifurcation stenting with 2 DESs. Major adverse cardiac events (MACEs) were defined as cardiac death, acute myocardial infarction (AMI), and target vessel revascularization (TVR). Sixty-four (52%) patients underwent ''crush,'' 42 (34%) patients underwent T stent, and 18 (14%) patients underwent kissing stent. Major adverse cardiac events were observed in 19 patients (17%) at 1 year: 6 (5%) AMI, 13 (12%) TVR, and no deaths, and 29 patients (26 %) at a mean follow-up of 22 months: 7 (6%) AMI, 21 (19%) TVR, and 1 (1%) death. No statistically significant risk factors for long-term MACEs were identified. It appears that treating bifurcation lesions with 2 DESs when necessary can be performed with an acceptable MACE rate.
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Kanei et al. (2010) conducted a cohort in Coronary bifurcation lesions (n=124). Bifurcation stenting with 2 drug-eluting stents was evaluated on Major adverse cardiac events (cardiac death, acute myocardial infarction, and target vessel revascularization). Bifurcation stenting with 2 drug-eluting stents for coronary lesions was associated with a 26% rate of major adverse cardiac events at a mean follow-up of 22 months.
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