Key result
Valsartan and its fixed combination with hydrochlorothiazide significantly reduced systolic and diastolic blood pressure by a mean of 26.6 and 14.8 mm Hg, respectively, after 16 weeks of treatment.
Why the study?
Does valsartan monotherapy and its fixed combination with hydrochlorothiazide reduce blood pressure in patients with grade 1 and grade 2 hypertension?
RCT (n=365)
Open-label
randomized
Yes
Does valsartan monotherapy and its fixed combination with hydrochlorothiazide reduce blood pressure in patients with grade 1 and grade 2 hypertension?
Valsartan monotherapy and its fixed combination with hydrochlorothiazide significantly reduced systolic and diastolic blood pressure in patients with grade 1 and 2 hypertension over 16 weeks.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Чазова et al. (2017) conducted an RCT in Grade 1 and grade 2 hypertension (n=365). Valsartan and its fixed combination with hydrochlorothiazide was evaluated on Antihypertensive effect on BP levels, influence on aortal stiffness, decrease in central and peripheral BP, and impact on aortic augmentation index (Mean absolute decrease of SBP 26.6 mm Hg and DBP 14.8 mm Hg). Valsartan and its fixed combination with hydrochlorothiazide significantly reduced systolic and diastolic blood pressure by a mean of 26.6 and 14.8 mm Hg, respectively, after 16 weeks of treatment.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: