Comparison of two skin imaging analysis instruments: The VISIA ®from Canfield vs the ANTERA 3D® CS from Miravex

Background The skin imaging analysis instruments are widely used to record and measure the surface and subsurface skin conditions. The main aim of this study is to reveal the differences and correlations in measuring wrinkle, skin texture, coloration/evenness, vascular features, and pore between two commercially available instruments. Methods Twenty‐eight subjects were enrolled in the study. A 2*2 cm cardboard was used to make sure the two instruments analyze the same area. Pictures were taken and analyzed by theVISIA®from Canfield and theANTERA3D®CSfrom Miravex, in sequence. Results The spot, ultraviolet spot, brown spot, red area, texture values measured withVISIA®were positively correlated with age, while the pore and wrinkle values showed no significance. The wrinkle, texture, melanin, hemoglobin, pore index, pore volume values measured withANTERA3D®had a significantly positive correlation with age. The spot, brown spot values fromVISIA®were positively correlated with the melanin value fromANTERA3D®. Texture value measured with the two instruments revealed positive linear correlation. Strong correlation was found between the red area value fromVISIA®and the hemoglobin value fromANTERA3D®. Ultraviolet spot fromVISIA®showed no linear correlation with the melanin value fromANTERA3D®. Neither of the wrinkle and pore measured with the two instruments showed linear correlation. Conclusions ANTERA3D®relies on multidirectional illumination obtained byLEDs of different wavelengths from different directions which make it advanced at the qualitative evaluation of various dermatologic conditions. Compared withVISIA®,ANTERA3D®is more sensitive in the assessment of wrinkle and it may also be available to evaluate the aging‐related enlarged pore.