Key result
Among patients with pulmonary hypertension undergoing right heart catheterization, those with pulmonary arterial hypertension were significantly younger and had fewer comorbidities, particularly atrial fibrillation, compared to non-PAH patients.
Why the study?
PAH is an uncommon, difficult-to-recognize condition with limited evidence in Asian populations.
Observational (n=79)
No
In a Thai cohort of patients undergoing right heart catheterization, PAH was the most common etiology of pulmonary hypertension, and echocardiographic TRVmax correlated strongly with invasive mPAP.
Aim: Pulmonary arterial hypertension (PAH) is an uncommon and difficult-to-recognize condition. There is still limited evidence on Asian populations. This study aimed to clarify the clinical characteristics of pulmonary hypertension (PH) patients who underwent right heart catheterization (RHC). Setting and Design: A single-centre retrospective observational analysis. Methods and Material: An observational analysis of adult patients diagnosed with PH by RHC from 2015 to 2019; clinical characteristics and investigations were recorded and compared between PAH and non-PAH. The correlations between maximal tricuspid regurgitation velocity (TRVmax) and mean pulmonary arterial pressure (mPAP) were also estimated. Results: From a total of 243 RHC patients, 79 PH patients were enrolled. The mean (SD) age was 56 (19) years. Dyspnea on exertion (DOE) was the most common clinical manifestation; 70 (89%). Most of them were in functional class II; 58 (73%). PAH was the most prevalent PH group; 46 (58%), followed by PH due to left heart disease; 26 (33%). In the PAH group, congenital heart disease-associated PAH was the most common aetiology; 25 (54%). Compared with the non-PAH group, PAH patients were younger and had fewer comorbidities, particularly atrial fibrillation. There were strong correlations between TRVmax and mPAP (r = 0.62, P < 0.01). Conclusion: PAH was the most prevalent among PH who underwent RHC. The most common presentation of PH patients was DOE. There were strong correlations between parameters from echocardiography and RHC (TRVmax and mPAP).
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Chiansirikraivuti et al. (2022) conducted an observational in Pulmonary hypertension (n=79). Pulmonary arterial hypertension (PAH) vs. Non-PAH pulmonary hypertension was evaluated on Differences in clinical characteristics (e.g., mean age) (p=<0.01). Among patients with pulmonary hypertension undergoing right heart catheterization, those with pulmonary arterial hypertension were significantly younger and had fewer comorbidities, particularly atrial fibrillation, compared to non-PAH patients.
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