A number of 3‐amino‐2,4(1H,3H)‐quinazolinediones were synthesized from o‐aminobenzoylhydrazines and ethyl chloroformate in pyridine or from 2‐methoxycarbonylphenyl isocyanate and 1,1‐disubstituted hydrazines. Four of the ten compounds screened exhibited anticonvulsant activity in mice.
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Kornet et al. (1984) studied this question.