Generalised amyloidosis and acute liver haemorrhage in four cats

Over a period of three years, four domestic shorthaired cats from a breeding colony were presented with a history of acute collapse or short illness leading to euthanasia. Post mortem examinations and histopathology revealed generalised amyloidosis, with severe hepatic involvement and associated liver haemorrhage. The clinicopathological findings are detailed and compared with existing reports of this unusual manifestation of amyloidosis in the cat.