Key result
Enhanced external counterpulsation may exert its benefits through enhanced diastolic flow, changes in the neurohumoral milieu, and load-independent changes in ventricular function.
Why the study?
What are the proposed mechanisms of action for enhanced external counterpulsation (EECP)?
What are the proposed mechanisms of action for enhanced external counterpulsation (EECP)?
The efficacy of enhanced external counterpulsation may be explained by enhanced diastolic flow, neurohumoral changes, and load-independent ventricular function changes, though further clinical studies are needed.
Proposed EECP mechanisms are hypothesis-generating; leaves open prospective validation in outcome trials.
The mechanisms accounting forthe salutary benefits of enhanced external counterpulsation (EECP) remain largely unknown. Emerging data now point to three possible hypotheses to explain its efficacy. These possible explanations include enhanced diastolic flow, changes in the neurohumoral milieu, and changes in ventricular function independent of changes in cardiac load. While each of these three hypotheses may help explain the mechanism behind EECP's effects, more clinical studies are required to refine these proposed explanations.
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Arthur M. Feldman (2002) reported a review. Enhanced external counterpulsation (EECP) was evaluated. Enhanced external counterpulsation may exert its benefits through enhanced diastolic flow, changes in the neurohumoral milieu, and load-independent changes in ventricular function.
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