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Switched on: The fluorescence emission of a DNA-based optical switch can be reversibly switched from blue to green using modulating light of different wavelengths (see picture). The device is based on the hybridization of two pyrene-functionalized DNA strands in the presence of a photochromic azobenzene-containing effector ligand. Hybridization occurs only with the cis-configured ligand, and results in pyrene excimer fluorescence.
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Uno et al. (2009) studied this question.
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