Key result
Following comprehensive stage 2 palliation for hypoplastic left heart syndrome, QRS duration change differed significantly between survivors (0.9 ± 7.1 ms) and non-survivors (-7.1 ± 10.0 ms).
Why the study?
How does QRS duration change across stages of hybrid palliation in patients with HLHS, and is it associated with mortality?
Population
54 patients with hypoplastic left heart syndrome who underwent hybrid procedure between 2002 and 2009…
Comparison
Hybrid palliation vs Survivors of Fontan completion vs non-survivors
Design
Cohort
Follow-up
From birth to post-Fontan procedure
Authors
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QRS shortening after stage 2 palliation was associated with mortality in HLHS; hypothesis-generating for QRS as a prognostic marker.
Cohort (n=54)
How does QRS duration change across stages of hybrid palliation in patients with HLHS, and is it associated with mortality?
Absolute Event Rate: 0.9% vs -7.1%
QRS duration increases progressively through hybrid palliation stages in HLHS survivors, whereas a decrease in QRS duration after comprehensive stage 2 may be associated with mortality.
Tsai et al. (2013) conducted a cohort in Hypoplastic left heart syndrome (HLHS) (n=54). Survival to Fontan completion vs. Non-survivors was evaluated on QRS duration change following comprehensive stage 2. Following comprehensive stage 2 palliation for hypoplastic left heart syndrome, QRS duration change differed significantly between survivors (0.9 ± 7.1 ms) and non-survivors (-7.1 ± 10.0 ms).
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