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Enzyme assays have been done on sonicated cells after separation from synovial fluid (I), supernatant synovial fluid (II), and sonicated whole synovial fluid including cells (III). 2 lysosomal enzymes (acid phosphatase and lysozyme), 2 glycolytic enzymes (lactic dehydrogenase and pyruvate kinase), and adenylate kinase levels were measured in each of the 3 samples from each synovial fluid. Rheumatoid and non-rheumatoid fluids were studied.
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Kerby et al. (1967) studied this question.
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