Solvation power of CO2-expanded solvents: Mid-IR spectroscopy is used in CO2-expanded solvents (see graphic) to investigate the molecular interaction between solute and solvent functional groups responsible for the differential solubility behaviour of acetaminophen, an analgesic drug, in “CO2-expanded ethanol” and “CO2-expanded acetone”.
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Sala et al. (2004) studied this question.
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