Key result
Two novel norovirus genomes isolated from brown rats in Hong Kong were approximately 7.5 kb in length and represent a novel cluster within genogroup V.
The discovery and genome sequencing of a novel norovirus strain in brown rats expands the known genetic diversity and host range of genogroup V noroviruses.
We report two genome sequences of novel noroviruses isolated from fecal swab specimens of brown rats in Hong Kong. The complete genome is approximately 7.5 kb in length and consists of 3 overlapping open reading frames encoding ORF1 polyprotein, VP1, and VP2, respectively. Sequence analysis suggested that these noroviruses should be classified in genogroup V, but they are distinct from other known rodent noroviruses and represent a novel cluster within the genogroup.
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Tse et al. (2012) studied Norovirus (n=2). Novel rat norovirus was evaluated on Genome sequence characteristics. Two novel norovirus genomes isolated from brown rats in Hong Kong were approximately 7.5 kb in length and represent a novel cluster within genogroup V.
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