Renal Function in Nephritis

In the last few years a vast amount has been written on the subject of renal function and the various methods of its estimation. Reviews of the literature have appeared frequently. The present paper is the report of a clinical study of renal function, involving 150 determinations by one of the newer methods—by an index of urea excretion which has been derived from Ambard's laws1by F. C. McLean.2 Ambard found that: 1. When the concentration of the urea in the urine is constant, the rate of excretion varies directly as the square of the concentration of urea in the blood. This law is expressed: 2. When the concentration of urea in the blood is the same, the rate of excretion varies inversely as the square root of the concentration in the urine. Introducing this factor into the first law we have: 3.Other factors remaining