Polymyositis (PM) and dermatomyositis (DM) are inflammatory muscular diseases of unknown cause. An immune mechanism may cause these inflammatory myopathies.'2 The mainstay of therapy in inflammatory myopathies is corticosteroids.3 In patients who are resistant to corticosteroids, many therapies are available: immunosuppressive drugs, plasmapheresis, or total body irradia- tion.4 These therapies are not always effective and may be responsible for certain serious side effects.
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Chérìn et al. (1994) studied this question.
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