SINCE ITS INTRODUCTION in 1933 (1) considerable attention has been given the product dihydrotachysterol or A.T.Io (antitetanisches Praparat Nr.Io). Holt (2, 3) found it would relieve the tetany in parathyroidectomized animals and keep the blood calcium apparently normal, and the literature contains a number of articles attesting to its effectiveness in the treatment of hypocalcemia of hypoparathyroidism (4–28). The reports in the American literature dealing with the clinical use of dihydrotachysterol are still few in number. Hence, it was felt desirable to report our clinical expert ence with the preparation in the management of a case of idiopathic hypecalcemia, probably of hypoparathyroid origin. History. A 54 year old Jewish housewife was admitted to the Jewish Hospital on November 28, 1938. Twelve years prior to admission she had experienced rather sudden spontaneous menopausal changes with which were associated few symptoms. However, complaints such as tiredness, weakness, ‘dragging down’ feeling and an inability to carry on as well as formerly dated from this time despite frequent medical attention.
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Jack Edward Berk (1939) studied this question.