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January 1, 2003The Journal of AntibioticsOpen Access

Takanawaenes, Novel Antifungal Antibiotics Produced by Streptomyces sp. K99-5278: I. Taxonomy, Fermentation, Isolation and Biological Properties

Yong-Pil Kim Hiroshi Tomoda Kousuke Iizima Takashi Fukuda Atsuko Matsumoto Yōko Takahashi Satoshi Ōmura

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Abstract

Three new pentaene macrolides having a 28-membered ring, designated takanawaenes A, B and C, were isolated from the fermentation broth of Streptomyces sp. K99-5278 by solvent extraction, silica-gel column chromatography and HPLC. Takanawaenes showed antifungal activity against Aspergillus niger, Mucor racemosus, Candida albicans and Saccharomyces cerevisiae.

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Kim et al. (2003) studied this question.

synapsesocial.com/papers/6a9fcdcd16360f1e481de4b2 https://doi.org/10.7164/antibiotics.56.448

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