Die technische Herstellung von klinischem dextran durch gelenkte synthese in wachsender Kultur

A process is described for the production of a specific‐molecular‐weight dextran, e.g. clinical dextran, by using a modified form of controlled synthesis. The synthesis is carried out directly in a medium containing appropriate amounts of sucrose and low‐molecular‐weight dextran after inoculation with a culture of actively growing bacteria. The importance of an inoculum substantially freed from substances affecting the synthesis of dextran is demonstrated. The technique appears to offer a decided advantage over other well‐known procedures. Technical details of the process and equipment are given.