What is the clinical evidence from this study?

Study design: Case Report. Population: Atrial flutter (n=1). Intervention: Flecainide acetate. Primary outcome: ECG changes (pseudo infarction pattern).

What question did this study set out to answer?

To document a case of flecainide-induced electrocardiographic changes mimicking acute myocardial infarction in an elderly patient treated for atrial flutter.

January 1, 1992European Heart Journal

Pseudo infarction ECG pattern occurring during intravenous treatment with flecainide acetate

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Key result

Intravenous flecainide acetate induced a pseudo infarction ECG pattern characterized by increased QRS duration, deep Q waves, and marked ST elevation in leads V1 to V4.

Population

79-year-old woman with atrial flutter and anginal complaints unresponsive to digoxin and verapamil

Design

Case_report

Authors

KAK. J. J. C. M. VAN AUBELMedisch Centrum Alkmaar JRJ.H. RuiterRoyal Perth Hospital AAAlfred ArnoldKing's Fund

Discussion

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Implication

Flecainide-induced pseudo-infarct ECG changes should be recognized to avoid misdiagnosing STEMI; this case leaves open incidence and predictors.

Key Points

To document a case of flecainide-induced electrocardiographic changes mimicking acute myocardial infarction in an elderly patient treated for atrial flutter.
Clinical evaluation and cardiac monitoring of a 79-year-old woman presenting with atrial flutter unresponsive to digoxin and verapamil.
Serial electrocardiographic assessment during and following intravenous flecainide acetate administration across two hospital admissions.
Intravenous flecainide administration caused marked widening of the QRS complex, deep Q waves, and pronounced ST-segment elevation in leads V1 to V4.
Acute myocardial infarction was ruled out, with identical pseudo-infarction ECG abnormalities recurring upon flecainide readministration on a second admission.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 79-year-old woman presenting with atrial flutter and anginal complaints.

Intervention

Intravenous flecainide acetate

Outcome

Development of pseudo infarction ECG pattern (significant increase in QRS duration, prominent deep Q waves, and marked ST elevation in leads V1 to V4)safety

Intravenous flecainide acetate can induce a pseudo infarction ECG pattern with marked ST elevation and deep Q waves, which clinicians should recognize to avoid misdiagnosis of acute myocardial infarction.

Cite This Study

AUBEL et al. (1992) conducted a case report in Atrial flutter (n=1). Flecainide acetate was evaluated on ECG changes (pseudo infarction pattern). Intravenous flecainide acetate induced a pseudo infarction ECG pattern characterized by increased QRS duration, deep Q waves, and marked ST elevation in leads V1 to V4.

synapsesocial.com/papers/6a9fd1934b4a72036190dfa5 https://doi.org/10.1093/oxfordjournals.eurheartj.a060034

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Implication

Flecainide-induced pseudo-infarct ECG changes should be recognized to avoid misdiagnosing STEMI; this case leaves open incidence and predictors.

Pseudo infarction ECG pattern occurring during intravenous treatment with flecainide acetate

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Pseudo infarction ECG pattern occurring during intravenous treatment with flecainide acetate

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider