Research Article Inflammatory response genes differentially expressed in a Colombian university cohort with alcohol consumption problems

with a decrease in individuals with problematic alcohol consumption.The relative transcription of SNCA increased in men, whereas there were no changes in women.Nevertheless, there were no significant differences observed in the SNCA, IL6R1, and TNFR1 proteins, whereas MIF was decreased in the overall sample.On the other hand, SNCA, IL6R1 and MIF proteins showed differences in men.We observed disparities in the expression of these inflammatory response genes when comparing controls and cases.These findings demonstrate that SNCA, IL6R1, and MIF are candidates for further study as potential therapeutic targets in disease conditions related to alcohol abuse.