N-Aryl-9-amino-Substituted Acridizinium Derivatives as Fluorescent “Light-Up” Probes for DNA and Protein Detection

This is the authors' abstract. We don't add key points for this paper.

[reaction: see text] N-Arylamino-substituted acridizinium (benzo[b]quinolizinium) derivatives are almost nonfluorescent in water or organic solvents; however, upon addition of calf thymus DNA or bovine serum albumin the fluorescence intensity increases by a factor of 10 to 50. Thus, these dyes exhibit ideal properties to be used as DNA- and protein-sensitive "light-up probes".