Key result
Experimental infection of day-old chickens with fowl aviadenovirus strains resulted in up to 50% mortality and clinical chemistry changes that paralleled macroscopical and histopathological lesions.
Population
Day-old specific pathogen-free chickens
Comparison
Oral inoculation with five fowl aviadenovirus… vs Control group
Design
Preclinical
Follow-up
up to 10 days post-infection
Authors
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Supports plasma markers for monitoring inclusion body hepatitis in chickens; hypothesis-generating in this Level 5 model.
Clinical chemistry analytes such as AST, GLDH, bile acids, and lipase are valuable tools for evaluating and monitoring the progression of inclusion body hepatitis in chickens.
Matos et al. (2016) studied Inclusion body hepatitis (IBH). Fowl aviadenovirus (FAdV) strains vs. Control group was evaluated on Mortality and clinical chemistry analytes. Experimental infection of day-old chickens with fowl aviadenovirus strains resulted in up to 50% mortality and clinical chemistry changes that paralleled macroscopical and histopathological lesions.
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