Key result
Perceived chronic stress shows a U-shaped relationship with resting-state activation of approach motivation.
Observational
The study demonstrates a U-shaped relationship between chronic stress and resting-state approach motivation, highlighting the importance of assessing baseline neural states in stress adaptation.
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Baseline neural assessment may refine stress evaluation; leaves open causal effects on outcomes and requires prospective validation.
< 0.05). These findings suggest that there is a nonlinear relationship between chronic stress and approach motivation, i.e. at both low and high chronic stress levels, resting-state activation of approach motivation is enhanced, whereas at moderate chronic stress levels, approach motivation is reduced, probably reflecting more efficient allocation and conservation of brain resources. More importantly, our findings demonstrate the necessity of examining the baseline neural state in addition to the task-evoked responses when assessing stress-related changes of approach motivation, thereby providing novel insights into the mechanisms of stress adaptation and their implications for psychological health.
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Xi et al. (2026) conducted an observational in Perceived chronic stress. Perceived chronic stress was evaluated on Resting-state activation of approach motivation (p=< 0.05). Perceived chronic stress demonstrated a U-shaped, nonlinear relationship with resting-state activation of approach motivation (P<0.05).
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