Experimental study demonstrates catalyst-free vicinal dichlorination of aliphatic alkenes under blue light, indicating a mild, functional-group-tolerant synthetic pathway.
A catalyst-free visible-light-induced dichlorination of alkenes has been developed using an N-chloro(fluorenone imine) reagent. The reaction proceeds through direct photoexcitation of the reagent under blue-light irradiation and enables vicinal dichlorination of aliphatic alkenes under mild conditions. Unprotected hydroxy and amino groups were tolerated, and comparable reactivity was observed under air. EPR analysis supported photoinduced N-Cl bond homolysis and was consistent with iminyl radical formation.
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Shimizu et al. (2026) studied this question.
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