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September 8, 2026Autism

Emerging Personality Pathology in Adolescents With Autism Spectrum Disorder: Clinical Correlates and Assessment Implications

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Authors

GDGiacomo DistefanoSBStefano BerloffaGSGianluca Sesso

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Overview

Observational study reveals high rates of dysfunctional personality traits in autistic adolescents, indicating the need for early developmental assessments.

Key Points

  • Investigate the prevalence of dysfunctional personality traits and evaluate their links to psychiatric comorbidities, clinical severity, and psychosocial functioning in adolescents with autism spectrum disorder.
  • Assessed N=79 adolescents with autism spectrum disorder without intellectual disability (mean age = 15.15 ± 1.50 years; 45.6% females).
  • Conducted multimodal diagnostic evaluations using the ADOS-2, ADI-R, WISC-IV/WAIS-IV, SCID-5-PD, K-SADS-PL, and standardized questionnaires.
  • Dysfunctional personality traits (DPTs) were identified in 64.5% of participants (75.0% in females vs. 48.9% in males), with prior ASD diagnoses missing in 62% overall and significantly more absent in females (OR = 2.86, p = .030).
  • Cluster A traits were most frequent (38.0%; schizoid 22.8%), while Cluster B borderline traits were significantly more prevalent in females than males (22.2% vs. 2.3%, p = .006).
  • DPT presence significantly correlated with lower functioning on the Children’s Global Assessment Scale (p = .037) and higher severity on Clinical Global Impression scales (p < .019) after FDR correction.

Cite This Study

Distefano et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd77658e84d0ff5b4629ahttps://doi.org/10.1177/13623613261476742
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