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September 8, 2026JEADV Clinical PracticeOpen Access

Use of a Bacteriophage Lysin to Control Axillary Malodor

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Authors

MSMaurice A. M. Van SteenselFHFabian HiaMBMei Zhen Beh

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Overview

Consumer trial demonstrates rapid axillary malodor reduction and microbiome preservation in humans, highlighting the potential of targeted lysins for personal care.

Key Points

  • To evaluate the safety and efficacy of a recombinant bacteriophage lysin in reducing axillary malodor and to determine its impact on skin microbiome diversity.
  • Conducted a human consumer trial to test the deodorizing efficacy of a proprietary recombinant lysin.
  • Performed supportive in vitro and in vivo safety evaluations along with skin microbiome profiling.
  • Application of the recombinant lysin produced rapid and sustained reduction in axillary malodor (numerical effect sizes not reported).
  • Treatment caused no skin irritancy and successfully preserved overall skin microbiome diversity.

Cite This Study

Steensel et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd7d558e84d0ff5b46e1ehttps://doi.org/10.1002/jvc2.70384
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