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September 8, 2026Acta Oto-Laryngologica

Segmentation-guided peritumoral radiomics and machine learning for ultrasound-based classification of salivary gland tumors

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Authors

HCHung-Wei ChenCCChin-Huan ChangWHWei-Chen Hung

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Overview

Diagnostic modeling study demonstrates accurate classification of salivary gland tumors using ultrasound radiomics, indicating clinical utility for preoperative noninvasive decision-making.

Key Points

  • To develop and validate a segmentation-guided machine learning framework utilizing peritumoral radiomic features to differentiate benign from malignant salivary gland tumors on ultrasound.
  • Trained a YOLOv8 deep learning model for automated tumor segmentation and extracted peritumoral radiomic features from ultrasound scans.
  • Screened and selected 12 radiomic features to train machine learning classifiers, evaluating them on testing and validation cohorts (validation n = 51, collected January–December 2025).
  • Constructed and deployed the full diagnostic pipeline into standalone and web-based applications.
  • The YOLOv8 segmentation model achieved Dice coefficients of 0.9485 in the training cohort and 0.8896 in the testing cohort.
  • Support Vector Classifier emerged as the best-performing model, yielding an AUC of 0.8117 in the testing cohort.
  • In the external validation cohort (n = 51), the Support Vector Classifier maintained an AUC of 0.7951.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd80458e84d0ff5b4730dhttps://doi.org/10.1080/00016489.2026.2722468
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