What does this research mean for the field?

Cotinus coggygria Scop. aqueous extract protects against ethanol-induced kidney and small intestine damage in rats by suppressing the abnormal increase in glycoprotein levels (sialic acid, hexose, and hexosamine). Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the protective effects of Cotinus coggygria Scop. aqueous extract against ethanol-induced kidney and small intestine damage by measuring tissue glycoprotein components in rats.

September 8, 2026Journal of the Turkish Chemical Society Section A ChemistryOpen Access

Glycoprotein Levels in Rats with Ethanol-Induced Kidney and Small Intestine Injury: Protective Effects of Cotinus coggygria Scop.

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To evaluate the protective effects of Cotinus coggygria Scop. aqueous extract against ethanol-induced kidney and small intestine damage by measuring tissue glycoprotein components in rats.
Six- to eight-month-old male Sprague Dawley rats were assigned to four groups: control, 50 mg/kg C. coggygria aqueous extract, 1 mL absolute ethanol, and extract pretreatment administered 1 hour prior to 1 mL absolute ethanol.
Treatments were delivered by gavage, and kidney and small intestine tissues were harvested under anesthesia 1 hour following ethanol administration.
Biochemical assays measured tissue levels of glycoprotein markers, specifically sialic acid, hexose, and hexosamine.
Administration of absolute ethanol significantly increased sialic acid, hexose, and hexosamine levels in both kidney and small intestine tissues.
Pretreatment with C. coggygria aqueous extract significantly suppressed the ethanol-induced elevations of sialic acid, hexose, and hexosamine, attenuating acute tissue damage.

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Implication

Experimental animal study reveals that Cotinus coggygria extract mitigates ethanol-induced glycoprotein alterations in rat kidneys and intestines, suggesting protective antioxidant properties.

Cite This Study

KARAKUŞ et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd83b58e84d0ff5b47a1c https://doi.org/10.18596/jotcsa.1932574

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Implication

Experimental animal study reveals that Cotinus coggygria extract mitigates ethanol-induced glycoprotein alterations in rat kidneys and intestines, suggesting protective antioxidant properties.

Glycoprotein Levels in Rats with Ethanol-Induced Kidney and Small Intestine Injury: Protective Effects of Cotinus coggygria Scop.

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Discussion

Implication

Cite This Study

Glycoprotein Levels in Rats with Ethanol-Induced Kidney and Small Intestine Injury: Protective Effects of Cotinus coggygria Scop.

Key Points

Discussion

Implication

Cite This Study

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