Enantiomerically pure compound synthesis by asymmetric glyoxylate–ene reaction with vinylic sulfides and selenides catalysed by a chiral titanium complex

Asymmetric catalysis of the glyoxylate–ene reaction with vinylic sulfides and selenides by a binaphthol-derived titanium complex provides enantiomerically pure (e.p.) diastereoisomers (anti and Z) of β-alkyl-α-hydroxy esters.