Key result
Spinal anaesthesia was performed safely without subsequent epidural haematoma in a patient on dual antiplatelet therapy following a prior platelet transfusion.
Why the study?
Can spinal anaesthesia be safely administered with prior platelet transfusion in patients on dual antiplatelet therapy?
Case Report (n=1)
No
Can spinal anaesthesia be safely administered with prior platelet transfusion in patients on dual antiplatelet therapy?
Regional anaesthesia may be considered in selected patients on dual antiplatelet therapy when deemed necessary, provided prior platelet transfusion is administered.
Answers are grounded in this paper and cite their sources.
May support cautious spinal anaesthesia after platelet transfusion in select DAPT cases; leaves open need for prospective safety data.
Complications relating to spinal anaesthesia following antiplatelet therapy are unclear. We report on a patient with a known history of chronic obstructive airway disease with respiratory tract infection who presented for emergency pseudoaneurysm repair. He underwent recent coronary stent implantation and was treated with clopidogrel and aspirin. Despite dual antiplatelet therapy, spinal anaesthesia was administered safely with prior platelet transfusion. Therefore, regional anaesthesia can be considered in selected patients with prior platelet transfusion on dual antiplatelet drugs when it is deemed to be necessary.
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Nath et al. (2013) conducted a case report in Pseudoaneurysm requiring urgent surgery in a patient with recent coronary stent on dual antiplatelet therapy (n=1). Spinal anaesthesia with prior platelet transfusion was evaluated on Safety of spinal anaesthesia (absence of epidural haematoma). Spinal anaesthesia was performed safely without subsequent epidural haematoma in a patient on dual antiplatelet therapy following a prior platelet transfusion.
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