Novel Strategies for Immunomodulation after Trauma: Revisiting Hypertonic Saline as a Resuscitation Strategy for Hemorrhagic Shock

From the Department of Surgery, Toronto General Hospital and University of Toronto, Toronto, Ontario Canada. Submitted for publication February 23, 2000. Accepted for publication February 24, 2000. Supported, in part, by the Medical Research Council of Canada and the Defense and Civil Institute for Environmental Medicine. 1999 Fraser Gould Lecture presented at the Annual Meeting of the Trauma Association of Canada at the Royal College of Physicians of Canada, September 23–25, 1999, Montreal, Quebec, Canada. Address for reprints: Ori Rotstein, MD, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario EN9 232, Canada; E-mail: [email protected]