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January 1, 1980Eisei kagakuOpen Access

The Decrease of Tetrahydrocannabinolic Acid (THCA) in Cannabis Leaves during Storage

Mamoru Yotoriyama

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Abstract

Tetrahydrocannabinolic acid (THCA) in fresh cannabis leaves has been already known to convert to tetrahydrocannabinol (THC) by decarboxylation, and then to cannabinol (CBN) by further dehydrogenation. In the present study, THCA and THC in cannabis leaves under three different environmental conditions were determined by the combination of preparative thin-layer chromatography and gas-liquid chromatography. Over 50% of THCA in cannabis leaves under one kind of environmental condition was found to convert to THC in 5 days, while THCA was hardly converted to CBN or cannabinolic acid.

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Mamoru Yotoriyama (1980) studied this question.

synapsesocial.com/papers/6a9fe5b538b9addeebefd3a2 https://doi.org/10.1248/jhs1956.26.50

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