A double-blind trial of prednisolone in patients with rheumatoid arthritis using doses of zero, 3 mg and 5 mg is reported. Patients on a dose of 3 mg derived little sustained benefit but subjects on the higher dose showed some improvement which did not last more than two years. Mild suppression of the hypothalamo-pituitary-adrenal axis occurred in both steroid-treated groups.
No takes yet. Share an insight, caveat, or question.
Chamberlain et al. (1976) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: