Taurine and glycine were given to human subjects and the bile acids studied. Taurine (0.5 g × 3 daily) markedly increased the proportion of taurine conjugated bile acids, whereas glycine (7 g × 3 daily) did not change the bile acid pattern of the normal subject. The findings have been discussed in relation to conjugation of bile acids under normal and pathological conditions.
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Jan Sjövall (1959) studied this question.