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A clone encoding ovine preprogastrin was isolated from a sheep genomic library. The deduced 104 amino acid sequence of ovine preprogastrin was 92% and 68% identical to the sequences of bovine and human preprogastrin, respectively. While the similarity was greatest in the gastrin-17 sequence, and unexpected similarity was also observed in the N-terminus of mature progastrin.
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Moore et al. (1997) studied this question.
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