All articles of this category Improved synthetic methods for the preparation of three differently protected (2 S ,4 R )-4-hydroxyornithines (10, 16, 24) have been developed which obviously can be used for the construction of the other stereoisomers. Formation of the corresponding α, β-didehydroamino acid derivatives (4, 15, 22) and their enantioselective hydrogenation are the characteristic steps of these syntheses.
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Schmidt et al. (1991) studied this question.