Concentrations of cyanocobalamin (vitamin B 12 ) ranging from 0.64‐186.6 μg/100g (fresh weight‐edible tissue) were determined for seven different varieties of seafoods by two radioisotope dilution (RID) methods. The correlation coefficient for 156 RID seafood assays using both techniques was 0.99 and the mean relative standard deviation for samples was 12.05 ± 5.19%. The reproducibility and comparability of the two RID assays was attributable to the uniform implementation of a rigorous extraction procedure which isolated cyanocobalamin in an aqueous phase prior to radiometric evaluation.
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Robert A. Beck (1979) studied this question.
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