The cyclic organometallic intermediates formed via CuCl-mediated highly regio- and stereoselective carbomagnesiation of 2,3-allenols with Grignard reagents may smoothly react with carbon dioxide to afford 2(5H)-furanones. A dramatic effect of the halide anion from the Grignard reagent (Br vs Cl) for CO(2) activation was observed. The reaction proceeded smoothly under mild conditions to afford the products in 58-93% yields.
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Li et al. (2013) studied this question.
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