Two novel drimane sesquiterpenoids, strobilactones A (3) and B (4), were isolated fromthe organic extract of a liquid culture of Strobilurus ohshimae. The structures of 3 and 4 were determined by spectroscopic methods. Compounds 3 and 4 exhibit cell growth inhibitory activities against cultured COLO 201 cells. Compound 4 also shows antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa.
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Shiono et al. (2007) studied this question.