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The role of glucan in stimulation of immune reactions has been well-established.In this report, we focused on the antibody production in glucan-supplemented children with chronic respiratory problems.We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effects of 100 mg d -1 oral dose of glucan.We found a significant increase in production of all tested antibodies in the glucan-stimulated group, but a decrease of antibody production in the control group.A thirty-day oral application of yeast-based natural immunomodulator β-glucan strongly stimulated the mucosal immunity of children with chronic respiratory problems.
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Větvička et al. (2013) studied this question.
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