Key result
Aorto-coronary bypass operations yielded a 10-year survival probability of 79% (vs 87% in a matched general population), with worse outcomes in patients with impaired left ventricular function.
Why the study?
What is the long-term survival of patients undergoing aorto-coronary bypass operations compared to a matched general population?
Cohort (n=1,041)
What is the long-term survival of patients undergoing aorto-coronary bypass operations compared to a matched general population?
Aorto-coronary bypass surgery provides good long-term survival, though outcomes are less favorable in patients with impaired left ventricular function or extensive vascular disease.
Answers are grounded in this paper and cite their sources.
Survival data inform post-bypass counseling with added caution for impaired LV function; extends Level 3 evidence while leaving optimal management open.
To evaluate longterm survival, 1041 consecutive patients with aorto-coronary bypass operations were followed for a mean of 7.5 years (range 5 to 14.5). The peri-operative mortality was 12 (1.2%). Of the 131 late deaths, 97 (74%) were cardiac in origin. The survival probability at 5 years was 92 +/- 2% and at 10 years 79 +/- 4%. Figures for a matched general Dutch population are 94% and 87%, respectively. Stepwise multivariate analysis revealed an association between death rate and impaired left ventricular function (rate ratio impaired function versus normal: 1.82, P = 0.0007) and extent of vascular disease (rate ratio 3 vessel-versus 1 vessel disease: 1.80, P = 0.01) while no relation was found with sex or age at operation. Surgery seems to provide a good probability of survival, although in patients with extensive vascular involvement and/or a decreased left ventricular function at the time of operation, the longterm outlook is less favourable than for those without these characteristics.
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Laird‐Meeter et al. (1987) conducted a cohort in aorto-coronary bypass operations (n=1,041). Aorto-coronary bypass operations vs. Matched general Dutch population was evaluated on Survival probability at 10 years. Aorto-coronary bypass operations yielded a 10-year survival probability of 79% (vs 87% in a matched general population), with worse outcomes in patients with impaired left ventricular function.
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