Key result
Intraoperative Diastolic Filling Index (DFI) was significantly higher in patent grafts (68.5%) compared to non-patent grafts (38.2%), suggesting a cut-off of >50% is useful for assessing graft patency.
Why the study?
Does the intraoperative Diastolic Filling Index (DFI) predict postoperative graft patency in patients undergoing CABG?
Observational (n=58)
No
Does the intraoperative Diastolic Filling Index (DFI) predict postoperative graft patency in patients undergoing CABG?
Absolute Event Rate: 68.5% vs 38.2%
p-value: p=<0.05
The Diastolic Filling Index (DFI) derived from electrocardiogram-gated intraoperative transit-time flow measurement is a useful and highly sensitive parameter for predicting early graft patency during CABG.
May aid intraoperative CABG graft assessment; hypothesis-generating in this cohort and requires prospective validation before clinical adoption.
簡便で信頼度・再現性が高いトランジットタイム法によるCABG術中グラフト血流分析において,心電図信号を同期入力することにより血流量の収縮期成分(Qs)と拡張期成分(Qd)を同定し,拡張期フィリング指数(DFI=100∫Qd/[∫|Qs|+∫|Qd|])が得られる.術中にMedi-Stim社製トランジットタイム血流量計で平均血流量(Qm)(ml/min)・拍動指数(PI)・機能不全率(INSUF)(%)・DFI(%)・F0/H1(血流曲線を高速フーリエ変換した基本周波数(F0)とその2倍周波数(H1)のパワー比)を求め,術後グラフト造影所見との関連を追究した.術後造影できたグラフト125本について,開存グラフト(120本)と非開存グラフト(5本)の間で,Qm・PI・INSUF・DFI・F0/H1すべての指標において有意差を認めた.DFI>50%は,他の指標のQm>15ml/min・PI<5・INSUF<15%・F0/H1>1.0とともにグラフト開存と術中に判断する有用な指標と考えられた.
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Takami et al. (2006) conducted an observational in Coronary Artery Disease undergoing CABG (n=58). Diastolic Filling Index (DFI) measurement vs. Non-patent grafts was evaluated on Diastolic Filling Index (DFI) in patent vs non-patent grafts (p=<0.05). Intraoperative Diastolic Filling Index (DFI) was significantly higher in patent grafts (68.5%) compared to non-patent grafts (38.2%), suggesting a cut-off of >50% is useful for assessing graft patency.
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